Coming into the game as number six seeds in the AFC, the Pittsburgh Steelers were always aware that this weekend's divisional playoff clash against the Denver Broncos was always going to be a tough game.
Things have just got a lot harder for Mike Tomlin and co., however, after it was revealed today that star Antonio Brown has been ruled out of the contest.
As reported by Fox Sports' Mike Garafolo, Pittsburgh's star wide receiver will not dress for the game against Denver having failed to progress through the NFL's concussion protocol this week.
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Brown's status has been in doubt ever since he was on the receiving end of a brutal late hit from Vontaze Burfict during the Steelers' Wild Card game against the Cincinnati Bengals last weekend.
And, although the AFC North franchise had been hopeful Brown would be ready to go after a week's rest, they will now have to take the next step towards Super Bowl 50 without their biggest offensive weapon.
The 27-year-old is coming off of a sensational regular-season in which he accrued 1,834 yards and 10 touchdowns, and he added another 117 receiving yards against the Bengals last week.
Responding to the news, the majority of NFL seem to feel the confirmation means only one thing. Here is a selection of the responses already appearing on social media:
One response Brown himself will be waiting for, however, will be that of Cincinnati star Adam "Pacman" Jones. The cornerback said this week that he'd only apologise to Brown if the WR didn't play versus Denver.
Over to you Pacman...
NFL fans: Can the Steelers still win without Brown? Have your say in the comments below...