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England seamer Steven Finn looks certain to miss the fourth Test against South Africa with a side strain.
Finn felt tightness in his left side during England's series-clinching victory at the Wanderers and was sent for scans on Sunday morning.
But head coach Trevor Bayliss was pessimistic about his prospects, paving the way for Chris Woakes, Chris Jordan or Mark Footitt to feature in Centurion, as England eye a historic 3-0 success.
"Steven is away getting scans but to be honest I doubt very much whether he'll be available for the next Test," Bayliss said.
"We'll have to wait and see how bad it is and make a decision on the one-day and Twenty20 series.
"But at this stage it looks like we have to make a replacement there heading into the last Test.
"That's unfortunate because I thought he was probably our most dangerous bowler in the first two Tests."
Finn missed the entire Pakistan series with a bone stress injury in his left foot and was not in the initial squad for South Africa.
But he proved his fitness during a stint with England Lions in Dubai and forced his way into the XI with a commanding display against South Africa A.
In the first three Tests, the 6ft 7in seamer took 11 wickets at an average of 26.09.