Cardiff Blues wing Tom James will make his first Wales appearance for more than five years in Sunday's RBS 6 Nations clash against Ireland.
And Wales head coach Warren Gatland has also handed starts to the likes of Blues full-back Gareth Anscombe, Scarlets prop Rob Evans and Ospreys flanker Justin Tipuric.
Wales captain Sam Warburton moves from openside to blindside flanker in Dublin, with a powerful bench featuring British and Irish Lions trio Alex Cuthbert, Gethin Jenkins and Dan Lydiate.
Centre Jonathan Davies, who missed the World Cup last autumn because of a knee ligament injury, is reunited in midfield with Jamie Roberts.
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