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Shaun Edwards says there is "no risk of complacency whatsoever" when Wales resume their RBS 6 Nations campaign on Saturday against opponents they have not lost against since 2007.
Warren Gatland's coaching reign at Wales has been notable for three Six Nations titles, two Grand Slams and a World Cup semi-final appearance.
But when it comes to dominance over one team during the Gatland era, then Wales can boast an invincible record against Scotland of played eight, won eight.
Lock Alun-Wyn Jones is the only Wales starting XV survivor from the one sunk by seven Chris Paterson penalties in a 21-9 defeat at Murrayfield nine years ago, while it is five years before then that Scotland last triumphed in Cardiff.
"We have a lot of respect for Scotland - they bring the best out of us," Wales assistant coach Edwards said.
"The teams that bring the best out of you are the teams that you know can hurt you. There is no risk of complacency whatsoever."
Despite a draw against Ireland in Dublin last Sunday, which ended Grand Slam and Triple Crown hopes at the first hurdle, Wales know that four successive victories - three of which would be at home - are likely to secure Six Nations silverware.
"It's still in our hands, that is what's good about it," Edwards added.
"If we had lost (against Ireland), then you have to rely on other teams to lose. If Ireland win every game, then we will have to beat them on points difference, but it's still in our hands."
Scotland backs coach Jason O'Halloran, meanwhile, insists the Dark Blues will not be happy just to put on an improved performance as they look to kick-start their campaign after last week's 15-9 Murrayfield loss to England.
He said: "We're disappointed as well after last week, but we need to channel that into a positive performance.
"I don't think we should ever be satisfied with a loss. It would be a real shame if we were happy to lose.
"The key thing is we learn from that loss and don't repeat history. Why are we losing these games and what do we need to do to improve? Those are the questions we need to answer.
"Once you do that it's about coming up with a strategy to give ourselves a better chance in the following contests."
The last time the Scots visited Cardiff they were shown little mercy after having Stuart Hogg red carded for a blatant shoulder barge into the face of Dan Biggar.
Now O'Halloran has urged the side to be on their best behaviour as they prepare to make their return to the Welsh capital.
"We need to control our mental state and not get frustrated," he said. "If we're in the game we need to look after the ball and make sure we do the things we want to do, and then hopefully those discipline issues won't be an issue for us and potentially will be for Wales."