A fan died of a heart attack during Borussia Dortmund's Bundesliga win over Mainz yesterday.
Another supporter also had to be resuscitated by medical staff, which prompted the crowd to watch the remainder of the match in virtual silence after news of the two separate incidents spread.
In a heart-warming act of support for the two stricken fans, those remaining at the Westfalenstadion launched into a rendition of 'You'll Never Walk Alone'. In another touching gesture, the referee opted not to add on any extra time out of respect to the two stricken fans.
A statement from Borussia Dortmund read: "During the game there were two tragic incidents in the stadium in which two spectators had to be resuscitated.
"Unfortunately one person did not make it and has died. We are full of sadness and the families are in our thoughts. We have received the news from the hospital that the condition of the second person is apparently stable."
Dortmund won the game 2-0 thanks to goals from Marco Reus and Shinji Kagawa. The victory means Thomas Tuchel's side maintain the gap at the top to Bayern Munich at five points with eight games to go.
BVB President Dr Reinhard Rauball added: “On behalf of Borussia Dortmund, I express my sincere condolences to the families of those affected and my deepest sympathy. Our thoughts are with them. We are also keeping our fingers crossed for all other patients, as well as for those who are so passionate about football.
You can check out the moving video of fans signing You'll Never Walk Alone in the video below.
Dortmund will next take to the field for the second leg of their Europa League clash against Tottenham, at White Hart Lane on Thursday. The German outfit hold a commanding 3-0 lead from the first leg, which came thanks to a brace from Marco Reus and an early Pierre-Emerick Aubameyang.