Everton's FA Cup hopes have taken a severe blow after it was revealed Seamus Coleman will not play in the semi-final against Manchester United.
The right-back joins Phil Jagielka, Gareth Barry, and John Stones in the treatment room, with the last three undergoing late tests.
More bad news
While Coleman is not having his best season at Goodison Park, this news is the last thing Roberto Martinez needs ahead of the make or break tie.
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All four are key players, and interestingly, with perhaps the exception of Barry, all are crucial to the Toffees' defence.
Their 4-0 humiliation in Wednesday's Merseyside derby does not bode well for the United game, and they could now have to face in-form Marcus Rashford with a makeshift defence.
18-year-old Callum Connolly and Tom Davies could feature under the famous arch, but with such a depleted Everton line-up, Louis van Gaal's side must be favourites.
Last time the two sides met in an FA Cup semi-final, Everton triumphed on penalties, with Jagielka netting the deciding spot-kick.
Right now, though, Everton are in crisis mode, knowing full well that only an FA Cup win can save their season.
Their league form has been disappointing to say the least, languishing in a thoroughly mediocre 11th place, 15 points off the European spots. Having come to expect Europa League football under David Moyes, there is no doubt that the club has taken a backwards step that is becoming increasingly difficult to reverse.
Martinez' job is under more scrutiny than ever, and if his side were to receive another drubbing like they did in midweek, it could spell the end of the Spaniard's time on Merseyside.
Should Everton sack Martinez? Have your say in the comments.