The Frenchman will now miss the rest of the Reds' season pending a full investigation by European football's governing body.
It's understood Sakho will accept his punishment after his initial sample tested positive for a substance on WADA's banned list. He failed to request for his B sample to also be tested by Tuesday's deadline.
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His absence will be sorely felt by Liverpool following his recent upturn in form, the 26-year-old helping Jurgen Klopp's side reach the Europa League semi-finals.
They face La Liga outfit Villarreal at El Madrigal on Thursday night in the first leg.
A number of teammates and pundits have commented on Sakho's actions, with club legend Jamie Carragher expressing disappointment in the defender.
He told Sky Sports: "It’s a nightmare for the player. I think he’s let himself down and the club badly, because he’s become a really important player.
"There's serious questions to be asked of him."
Sakho will now await his fate while UEFA further investigate his doping violation.
More to follow.