Wayne Rooney is one of six England players who is expected to drop to the bench for the final group game against Slovakia.
The Guardian report that Roy Hodgson is going to try out a new-look side as the Three Lions aim to seal qualification for the last-16, but he has made some huge calls in the process.
Rooney will be rested after pulling the strings in the midfield for the first two games against Russia and Wales, as in both games, he appeared to tire in the latter stages.
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That will allow Liverpool's Jordan Henderson into the first XI, where he will be paired not with Dele Alli, but Jack Wilshere.
Full-backs Kyle Walker and Danny Rose will also be rested, which suggests Hodgson's team selection isn't based purely on form, as Walker was man of the match against Wales.
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Nathaniel Clyne and Ryan Bertrand will come in to show what they can do in those positions.
And, as the fans have been demanding, Daniel Sturridge and Jamie Vardy will start instead of Harry Kane and Raheem Sterling.
Kane has so far failed to reproduce the form that won him the Premier League Golden Boot, while Sterling has continued to struggle just as he did for Manchester City in the second half of the season - prompting one fan to rather cruelly set up a JustGiving page to raise money to fly him home.
Hodgson has certainly sprung a surprise by making so many changes all at once, with Rooney being the biggest shock.
The captain's absence could leave England without much experience, though their less-seasoned players will now at least have had a runout should they be called upon later in the tournament.
Hodgson's side need to win the game to ensure they qualify as winners of Group B, which will land them a last-16 tie against a third-placed finisher from another group.
Speaking to the assembled press about his possible team selection, Hodgson admitted:
“It wouldn’t be a problem if I wanted to keep the same side but there are players who would like to play and have been knocking on the door to play.
"I have the option because everyone is anxious to show what they want to do. It’s a question of what we’d like to do, rather than what is necessary.”
Should Wayne Rooney start against Slovakia? Have your say in the comments.