Arsene Wenger will have feared the worst when Gabriel Paulista clutched his ankle in pain after a tackle with Manchester City's Kelechi Iheanacho on Sunday.
After losing the Brazilian, Arsenal now have limited options at centre-back heading into the new Premier League season, with Per Mertesacker also out injured and Laurent Koscielny only returning to training recently.
If you hadn't guessed it already, the Gunners have another injury crisis on their hands.
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Quite how Wenger will combat the worrying situation he finds himself in remains to be seen but, for Arsenal fans, the answer is simple: spend, spend, spend.
And it would seem the Frenchman might do just that after learning the extent of Gabriel's injury.
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According to revered BBC Sport journalist David Ornstein, Arsenal will be without the 25-year-old for up to eight weeks after suffering an ankle sprain.
He said: "Arsenal CB Gabriel out 6/8 weeks - ankle sprain. Not quite as bad as he first feared but #AFC stepping up pursuit of Valencia's Shkodran Mustafi."
Ornstein touches upon Arsenal's bid to sign Mustafi, who is reportedly available for £25 million.
Should Wenger indeed make an official move for the German, he would be acquiring a consistent and experienced centre-back capable of shoring up his leaky defence.
The Frenchman is certainly on the lookout for new additions anyway: "I've said many times that we are in the market.
"Of course it’s not an easy market for us. Let’s hope we have good news from Gabriel.
"Laurent Koscielny is back in training now but he might be short for next week. If Gabriel is out, Per Mertesacker is out and Koscielny not ready - that’s a lot of players."
What will worry fans most, though, is Arsenal's other reported target: Jonny Evans.
According to the Mirror, Wenger wants a new centre-back before his side's clash with Liverpool this weekend and could try to lure the former Manchester United defender from West Brom to satisfy that need.
Not quite what supporters had in mind.
Gabriel appears positive of what the future holds, at least, after posting a motivational picture on Instagram (see below).
No less than eight first-team players will be missing for the Gunners when they host Liverpool on Sunday at the Emirates Stadium, though Jurgen Klopp will also be without seven starters.