Henrikh Mkhitaryan is set to miss Armenia's World Cup qualifying fixture against Denmark on Sunday after picking up a thigh muscle injury.
The Armenian FA have now revealed that the midfielder will be out of action for up to 10 days after undergoing medical tests.
While it's now seemingly impossible that Mkhitaryan will play for his national side against Denmark, it's also extremely likely that he will miss next week's Manchester derby at Old Trafford.
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The 27-year-old still hasn't started a game under Jose Mourinho's guidance this term but made quite the impression from the bench against Hull City this past weekend.
Indeed, the ex-Borussia Dortmund man played a prominent role in guiding the Red Devils to all three points at the KCOM Stadium.
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Ultimately, though, it appears that Mourinho won't be able to unleash his summer signing against the Citizens next Saturday.
The Armenian FA released the following statement on their website:
As you know, August 31, in the Czech Republic and Armenia, the senior national team Henrikh Mkhitaryan named Armenia injury as a result was unable to continue the match. Henrikh Mkhitaryan has passed a medical examination Mlada Boleslav in one of the clinics. Unfortunately, the results are not encouraging. Mkhitaryan was found in the lower third of the left thigh muscle injury. Such injuries usually required for healing in a week to 10 days, which means that Mkhitaryan will miss the September 4 in Copenhagen, Denmark-Armenia match will be held at the stadium "Parken".
There's every chance, then, that Spaniard Juan Mata will keep his place in the starting XI for the fixture against City.
Jesse Lingard has been on the sidelines since picking up an injury in the Community Shield but could return to the team sooner rather than later, while Marcus Rashford, who netted United's only goal in the win over Hull, will be hoping for a starting place.
Memphis Depay has also struggled to claim a spot in the squad throughout the opening weeks of the campaign, but he will be looking to prove his credentials to his new manager.
Mkhitaryan's injury is a clear blow for the Portuguese tactician, but he will still have more than enough players to choose from.
Do you think Mata will keep his place in the team against City? Have your say below!