Like Jose Mourinho, Arsene Wenger faces a few selection dilemmas ahead of Manchester United vs Arsenal at Old Trafford on Saturday.
Alexis Sanchez is perhaps the Frenchman's biggest concern. Despite nursing a hamstring injury on international duty with Chile, the versatile winger played against Uruguay on Tuesday night and scored a brace.
His involvement riled Wenger, who had no choice but to put faith in Chile's medical staff and hope Sanchez returned to north London unscathed.
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And while he has, that doesn't mean to say he won't miss Saturday's clash.
"We will see if [Sanchez] can be involved or not," Wenger said, per the Daily Mail. "I will consider the risk of injury because he has played while recovering from a hamstring injury.
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"We were in doubt 24 hours before the game. We didn't know if he'd play or not. I will consider the way he feels as well."
Sanchez isn't Wenger's only worry, though, with Hector Bellerin out for four weeks with an ankle injury suffered against Tottenham two weeks ago.
The 21-year-old Spaniard has become indispensable at the Emirates Stadium and his absence could prove costly against Mourinho's men at the Theatre of Dreams.
Wenger must now choose his temporary replacement carefully, with Arsenal's manager considering three names to play at right-back - and Mathieu Debuchy, somewhat surprisingly, isn't one of them.
"We have players who have played plenty of games in the Premier League like [Carl] Jenkinson," he said in a pre-match press conference.
"We could also play Gabriel and [Francis] Coquelin has already played there.
"[Shkodran] Mustafi has played there, but I will not disturb a pair of centre-backs which works. I will keep what was strong before and try to a find good solution at right-back."
Jenkinson is the logical replacement, but 180 minutes' worth of football since January - he played a full 90 against Reading and Ludogorets - will concern Arsenal fans.
And so, with Coquelin a central midfielder by trade, Gabriel would arguably be Wenger's best option given his experience and pace.
The Brazilian, 25, still represents a risk because of his rash and tough-tackling approach, but history dictates Jenkinson shouldn't start such an important fixture so soon after recovering from a long-term injury.
It's a difficult situation to be in regardless.