It was a bad night for Tottenham on Tuesday. With defeat to Monaco the club saw their Champions League aspirations go up in flames and they will have to resume the now familiar path in the Europa League - though that's still not a given.
Fans had been hopeful of making it to the knockout stages of the Champions League, having been placed in a tricky but not impossible group alongside Bayer Leverkusen, Monaco and CSKA Moscow.
And Kane believes that he knows the reason why the club have struggled to make the grade in Europe this season, blaming Wembley as the cause of their poor home form.
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Spurs have lost both of their home games at Wembley so far, going down 2-1 to Monaco and losing 1-0 to Leverkusen earlier in the month.
The benefit of the move to the country's national stadium had been questioned almost constantly, and it now appears that Kane has joined the chorus by lamenting the fact that the club were unable to transform it into a fortress.
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"I think losing two of our home games in this competition, it's got to be a fortress at home. Although we are playing at Wembley this year, it's no excuse," he said via the Daily Mail.
"When teams come over to us, we have to make it difficult and use that to our advantage and we didn't."
Kane also bemoaned his side's ability to push on after restoring parity against Monaco, having felt that Spurs were good enough to get something from the game.
"It's always difficult away from home in the Champions League and Monaco knew what they had to do.
"It's disappointing, I don't think we were good enough today anyway, but we got ourselves back in the game at 1-1 but it was a schoolboy error to concede straight after.
"It took the stuffing out of us and obviously we didn't have enough to get back in the game.
'I don't think on the day we were good enough, we found it difficult to play from the back, they pressed us high but we are gutted.
"We wanted to go far in this competition. We will look back and say the home games is where we should have been better."
One more game
Tottenham are currently lying in third place in Group E with four points from their five games and can cement their place in the Europa League by avoiding defeat to bottom side CSKA Moscow in a fortnight's time.
However, given their struggles at their adopted home, it may be a tall order against a talented side playing for pride.
CSKA showed that they are capable of pulling off a result, by gaining a draw with Leverkusen in Moscow.
However, they left it late to bag the point with Bibras Natkho scoring a late penalty.
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