European champions Manchester United and rivals Liverpool were handed mouth-watering ties against Inter Milan and Real Madrid in the Champions League last 16 on Friday.
The draw pits United against Jose Mourinho's Italian giants Inter while Liverpool will take on nine-times winners Real, a club repeatedly linked with Reds boss Rafael Benitez.
Chelsea also face an intriguing reunion with former manager Claudio Ranieri after being paired with Juventus while Arsenal take on Roma.
Mourinho enjoyed success at Old Trafford during his time as Porto boss and then developed a strong rivalry with United boss Sir Alex Ferguson after moving to Chelsea.
There had been a possibility that United could draw Spanish champions Real, with whom tensions are high due to their pursuit of Cristiano Ronaldo, but Liverpool landed that prize.
It will be Liverpool's second visit to the Spanish capital this season after playing Atletico Madrid in the group stages.
Ranieri guided Chelsea to the semi-finals of the competition in 2004 but made way for Mourinho at Stamford Bridge later that year.
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