Republic of Ireland boss Giovanni Trapattoni ruled Damien Duff, Darron Gibson and Steven Reid out of his plans for Saturday's World Cup qualifier against Italy.
Injuries have accounted for the trio, with Fulham winger Duff suffering a calf problem, Gibson sidelined by groin trouble and Reid forced out with an Achilles blow.
Striker Caleb Folan had already been declared unavailable due to a hamstring injury.
The unbeaten Republic take on Group Eight leaders Italy at Croke Park knowing a victory would move them to within one point of top spot, with one round of matches remaining. Italy will secure their place in next year's finals if they avoid defeat.
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