Scunthorpe manager Nigel Adkins is hoping to have Cliff Byrne and Martyn Woolford back for the visit of Ipswich.
Byrne was brought off with a hamstring injury during last weekend's 1-1 draw at Reading but looks set to feature once again at right-back.
Woolford is training again after having stitches removed from a foot injury he picked up a month ago.
Joe Murphy looks set to return between the sticks after serving a one-match ban at the Madejski Stadium last weekend.
However, the Iron will be without long-term absentees Kenny Milne and Ben May.
Milne is on the comeback trail after two knee operations and May is still out with an ankle injury, although he is close to a return.
Ipswich manager Roy Keane has been hit by a double suspension blow.
The Blues will be without skipper Jon Walters and midfielder Grant Leadbitter at Glanford Park after both men picked up their fifth yellow cards of the season in the 3-1 victory against Blackpool last weekend.
Walters and Leadbitter will each serve one-match bans. However, the Tractor Boys could welcome defender Alex Bruce and winger Lee Martin back to the fold.
Bruce has been out for four weeks with a groin injury but may return, while Martin is hoping to recover from a heel injury in time to face the Iron.
Meanwhile, Keane will be buoyed by the news that David Norris came through 60 minutes of a friendly match this week.
Norris made his return from a knee ligament injury he picked up on the opening day of the season but it is thought the Scunthorpe clash will come to soon for him to feature.
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