Wales will not be at the 2018 World Cup in Russia after losing 1-0 at home to the Republic of Ireland on Monday night.
Chris Coleman's men reached the semi-finals of EURO 2016 but - without Gareth Bale for their crucial final group game - won't be repeating any of their heroics next summer.
James McClean scored the only goal of the game to secure Martin O'Neil's men a place in the play-off's, which will take place in November.
Some excellent work on the right flank by Burnley midfielder Jeff Hendrick set up the 28-year-old West Brom star to lash home a superb finish.
An onslaught was expected in the final 30 minutes at the Millennium Stadium but, in truth, the Welsh struggled to test Darren Randolph in the Irish goal.
Arsenal midfielder Aaron Ramsey was incredible at EURO 2016 but has struggled to replicate the same type of performances during the World Cup qualifying campaign.
"We're used to these situations," said the Arsenal star ahead of Monday night's game. "We put ourselves in these situations time and time again and we find a way, that's what's so special about this team.
"We wanted to finish off with two wins, we're halfway there. We wanted to go back to Cardiff with the three points and it's going to be a big game on Monday night.
"We know our fans are going to be magnificent on Monday and hopefully we can give them something to cheer about."
The 26-year-old had a great opportunity late on but - in Bale's absence - blasted his long-range free-kick way over the bar.
Coleman had pinned his country's hopes on Ramsey ahead of Monday night's game.
“If he’s [Ramsey] anywhere near his best we’ve got a chance of having a positive result,” said Coleman.
Despite being in excellent form at Arsenal, Ramsey was nowhere near his best and Twitter absolutely tore him apart for his unacceptable display.
Ramsey has paid the ultimate price for his poor performance against the Republic of Ireland - he'll have no part to play at next summer's World Cup.