It seems being knockout by Saul 'Canelo' Alvarez has had quite the effect on Amir Khan.The British boxer got his big chance to fight the Mexican in May 2016 after recovering from two defeats to Lamont Peterson and Danny Garcia in 2011 and 2012 respectively.Khan was defeated inside six rounds with a shattering knockout at the T-Mobile Arena in Las Vegas.His American trainer - Virgil Hunter - even advised against the fight, explaining:  “I let him know that was stupid, crazy. For what? The Canelo fight was a fight I was totally against."But once I saw it wasn’t going to change, I told him: ‘I can get you through this fight, but we don’t have any margin for error. You have to focus every second of every round. If you lose focus it could be disastrous for you.’"The bout eventually went ahead and the knockout was so devastating that Khan hasn't stepped between the ropes again, waiting helplessly for a high-profile return that simply hasn't arrived.The 30-year-old has been linked with the likes of Manny Pacquiao and Kell Brook during his time out of the ring.However, Khan has just fired up talks over the mother of all lucrative fights with none other than Floyd Mayweather.The Brit stated: "Floyd is a great fighter. I just have something he’s not faced, speed. Floyd knows I’m not the one to back down."It's been a year I've not fought due to hand surgery. I’m ready to make my comeback at 30 years of age. Say what you like Canelo was getting outboxed. I was winning on [the] cards. He had power and caught me with a huge right. That's boxing."Mayweather doesn’t have the power. In any fight I’ve never been outboxed. A Mayweather-Khan fight would be a game of chess. Speed, movement and accuracy will cause him problems."In taking the bold decision to tweet said quotes, Khan opened him up to boxing fans on Twitter and they didn't disappoint. Check out the pick of the replies:

Come on Amir, not only are we talking about one of the greatest pound-for-pounds of all time with a 50-0 professional record but he's freshly retired, for the second time.

Furthermore, if there's any chance that Money will emerge from his retirement once again, then Khan simply won't prove a lucrative enough challenge. 

Besides, let's be honest, that fight would only go one way.

Who do you think Amir Khan should fight next? Have your say in the comments section below.