Defenders Fabio Aurelio and Philipp Degen will both miss the Barclays Premier League clash at home to Bolton.
Aurelio has missed the last two matches with a minor knock while Degen (calf) did not play in the midweek goalless draw with Wolves.
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However, centre-back Daniel Agger returns to the squad after regaining fitness while captain Steven Gerrard has reported no after-effects from Tuesday night when he made his comeback after a hamstring problem.
A goalless draw against Wolves in midweek meant they fell three points behind fourth-placed Tottenham but Benitez agreed with captain Gerrard after the Wolves game when he said the side are heading in the right direction.
"All I can do is prepare my team properly, to analyse things and try to find solutions to the problems we have," said the Liverpool boss.
"Now we are not losing games and doing a little bit better we have to try to do the same.
"The players know we are improving. Like Stevie said before, maybe we have turned the corner."
Bolton manager Owen Coyle could be tempted to name an unchanged side.
On-loan winger Vladimir Weiss may have to settle for a place on the bench while another new recruit Stuart Holden has a slight thigh strain.
Mark Davies remains absent with an ankle injury as Bolton look to build on the win against Burnley.
Since Coyle switched clubs, Bolton have chalked up successive victories against his former side Burnley and Sheffield United after two defeats by Arsenal.
He believes his team will face Liverpool, who had to settle for a point against Wolves, with confidence especially after two clean sheets.
Coyle said: "We need to repeat our performances in the last two games. It is match to look forward to.
"My team will be going toe to toe with some of the best players in world football but have a chance to show they can play a bit as well.
"I have been delighted with the quality and application of the players. What we have to do is add to it.
"You do not come in with a magic wand. You come in with a recipe for hard work. There are areas we can work on to make us better as a group.
"We have managed to move out of the bottom three but only just. We are not kidding ourselves.
"We are not getting carried away. The hard work is ahead of us. It is a challenge we are up for."
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