Charlton manager Phil Parkinson could be without goalkeeper Rob Elliot and defender Frazer Richardson for the visit of Brighton.
The duo both picked up groin problems during their 2-0 victory over Yeovil on Saturday and are major doubts.
Should they not be passed fit Darren Randolph and Jose Semedo are the most likely to replace them in Parkinson's first XI.
Midfielder Johnnie Jackson was handed a starting role against Yeovil and should retain his place in Parkinson's side after joining on loan from Notts County.
Charlton will definitely be without Grant Basey who remains sidelined with ankle ligament damage, while Kelly Youga is still missing with a knee injury.
Striker David Mooney showed no ill-effects following a head injury against the Glovers and should keep his place in attack alongside Deon Burton.
Brighton boss Gus Poyet will be without the suspended Adam Virgo.
The defender was shown a straight red card following a clumsy challenge on Leeds' Max Gradel on Saturday and he will sit out the next four games, so Adam El-Abd is likely to take his place in the starting XI.
Only a last-minute Robert Snodgrass strike stopped the Seagulls from taking all three points away from Elland Road after Glenn Murray had given Brighton a 77th minute lead.
Veteran striker Nicky Forster was named on the bench at the weekend following a reported argument with Poyet, which has seen him sit out the past four matches, and it remains to be seen whether he will be handed a starting role.
Defender Colin Hawkins remains the only definite absentee following a heel operation.
Brighton remain undefeated on the road in their last six away league outings, collecting two wins and four draws.
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