Captain Rio Ferdinand has been ruled out of England's international against Egypt with a back injury.
The Manchester United defender will miss next Wednesday's game at Wembley after feeling a twinge in his back before Tuesday's Barclays Premier League match against West Ham.
That came just three games into his comeback from a long-standing back complaint which kept him out for more than three months.
United boss Sir Alex Ferguson immediately ruled Ferdinand out of Sunday's Carling Cup final and the 31-year-old also misses out on the chance of leading his country into their first game since John Terry was stripped of the captaincy.
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