Accrington manager John Coleman will be without goalkeeper Ian Dunbavin for the visit of promotion-chasing Rotherham to the Crown Ground.
Dunbavin was dismissed in Saturday's 2-1 win over Barnet for tripping midfielder Albert Adomah, meaning he will serve a one-game ban.
Deputy Dean Bouzanis will start in the 29-year-old's place, with Josh Molloy coming into the squad as cover.
Coleman will also be without Bobby Grant, who misses the clash with the Millers due to a hamstring injury.
James McCarten - on loan from Premier League side Everton - could be handed a debut after making the bench in Saturday's victory.
Injured defender Leam Richardson (groin) is unlikely to feature as Stanley look to haul themselves into play-off contention with a win.
Rotherham manager Ronnie Moore could hand a debut to on loan Reading midfielder Abdulai Bell-Baggie.
The 18-year-old winger arrived at the Don Valley Stadium on Friday but had to settle for a place on the bench as an unused substitute for the weekend's 1-0 win over Dagenham.
But Moore could throw the new arrival into the fray for the Millers second successive away game, with Bell-Baggie brought in to cover for the injured Paul Warne and Andy Liddle.
Craig McAllister - on loan from Exeter - made his full debut in Saturday's win and he is set to retain his place.
Moore still has concerns over a host of other players, including Nicky Law, who continues to struggle with a groin problem.
Gavin Gunning (thigh), Jamie Green (ankle) and Stephen Brogan (calf) are all unlikely to feature yet again.
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: https://www.givemesport.com/writeforgms