Rotherham could be without both first-choice central defenders against Macclesfield.
Nick Fenton will definitely miss out after injuring his calf in the 1-0 win against Bury at weekend and he will be out for two to three weeks.
And the Millers have a doubt over former Tranmere man Ian Sharps, who is nursing a hamstring problem.
Pablo Mills will come in for Fenton and boss Ronnie Moore will be forced into a reshuffle if Sharps is ruled out, with Gavin Gunning possibly moving into the centre of defence and Jamie Green coming in at left-back.
Experienced duo Paul Warne and Andy Liddell will play no part once again due to foot and Achilles injuries respectively as the Millers continue their push for automatic promotion.
Macclesfield could welcome back Izak Reid and Paul Bolland for the trip to promotion hopefuls Rotherham.
The duo both returned to training on Monday following their respective ankle and rib problems and they could earn a place on the bench if caretaker boss Gary Simpson deems them fit enough to play.
Carl Tremarco is pushing for a starting role after coming off the bench to make his return from a hernia problem, which kept him sidelined for a month and a half, in Saturday's 3-1 defeat at Dagenham.
Ricky Sappleton will undergo a knee operation on Tuesday and the club will have to wait for the outcome of that before learning the extent of the damage, which could potentially end the striker's season.
Colin Daniel (hamstring) is still three to four weeks away from a return, while long-term absentee Hamza Bencherif (ankle) remains sidelined.
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: https://www.givemesport.com/writeforgms