Shrewsbury captain Graham Coughlan is looking at around three or four weeks on the sidelines and will therefore miss Tuesday's visit of Cheltenham.
The centre-back sustained a tear to his thigh muscle during Saturday's 3-0 win at Crewe and was forced off at half-time, possibly signalling the end of his season.
But on a promising note, manager Paul Simpson is hopeful Kelvin Langmead could return from a rib injury against the Robins and act as a direct replacement at the heart of defence.
Striker Jamie Cureton is battling to overcome various bumps and bruises and should he not make it then youngster Tom Bradshaw, although unlikely to start, will have done his chances of involvement no harm at all.
The 17-year-old debutant signalled his arrival on the scene with a late brace to see off Crewe at the weekend having replaced Cureton as a 75th-minute substitute.
His chances are increased by Jake Robinson's enforced absence due to ligament damage. Midfielder Craig Disley (broken ankle) is back running again but the game against Cheltenham will come too soon for him.
Michael Townsend and Matt Thornhill will be assessed but the pair are both expected to be fine.
Centre-back Townsend recovered from an ankle knock sustained at Crewe on Easter Monday to start Saturday's emphatic 5-2 win over Bury, although he came off 10 minutes from time feeling the effects.
Midfielder Thornhill took a blow to his lower back/hip and was also forced off just after the break, but the pair should be okay to feature.
On-loan midfielder Aaron Lescott remains on the sidelines however with a knee problem that is also expected to keep him out of Saturday's trip to Rotherham. But he will be back in the frame next week.
Three successive wins combined with one defeat in their last six games has gone a long way to securing Cheltenham's Football League status but they are certainly not safe yet as teams around them at the foot of the table continue to pick up points.
Although a seven-point advantage over second-bottom Grimsby combined with a far superior goal difference and a game in hand at home to rock-bottom Darlington certainly makes the Robins favourites to avoid the drop.
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