Ben Youngs ruptured ligaments in his left knee early on in England's Six Nations opener with Italy, which has seen the scrum-half sidelined for four months, according to Sky Sports.
The Leicester Tigers man, who has 211 appearances for the Welford Road club since making his debut in 2006, got his leg trapped in a ruck as he sustained the damaged knee.
The 28-year-old was taken off on a stretcher after being given initial treatment on the pitch.
The Rugby Football Union released a statement on Monday saying that the Leicester half-back has "ruptured his MCL in his left knee and is having further assessment with a surgeon this week."
It's a major blow for Youngs, who has 73 appearances for the national side and has represented England at the last two World Cups.
He was also on the British & Irish Lions tours during 2013 and 2017 as well.
He has 211 appearances for Aviva Premiership side Leicester, for whom he has played 10 games for this season and scored one try.
Youngs' replacement will be Richard Wigglesworth of Saracens, whilst the only other specialist scrum-half currently in the squad is Danny Care. The latter is expected to take the no.9 shirt for this weekend's clash against Wales at Twickenham after replacing Youngs in the win against Italy.
Wigglesworth was first called up to the set-up in 2008, making his debut in the Six Nations against France that year. He has played for England at the last two World Cups and last made an appearance for the national side in 2017.
Wasps no. 8 Nathan Hughes and Exeter Chiefs' front-rower Luke Cowan-Dickie could potentially operate in Youngs' position, but it is not a perfect fit.
The former has not played a rugby match since December after damaging ligaments in a game versus Wasps earlier this season.
Jones has called-up Wigglesworth now to solve the current selection dilemma ahead of the challenging clash against Wales, who disposed of Scotland 34-7 last weekend.News Now - Sport News