Sheffield United trio Darius Henderson, Stephen Quinn and Lee Williamson could all undergo surgery before the last game of the season.
The Blades will bring the curtain down on a disappointing campaign at Ipswich on Sunday and all three players could be missing as they look to resolve long-standing injuries.
Midfielder Williamson, signed from Watford for around £500,000 last summer, has missed large chunks of the season due to a back problem.
Striker Henderson has a hernia and midfielder Quinn requires surgery to investigate a possible nerve problem in his foot, which has forced the Irishman to play through the pain barrier in recent weeks.
The Blades have been dogged by a long list of injuries to key players throughout the season, with manager Kevin Blackwell struggling on several occasions to name a full quota of substitutes on match day.
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