With so many top-class players lining up for each side, there are several enthralling individual battles worth keeping a watchful eye on.
Cristiano Ronaldo versus Virgil van Dijk, Luka Modric up against Jordan Henderson, Sergio Ramos tangling Roberto Firmino – the list goes on.
Probably the most pivotal match-up of all, though, is where Liverpool’s right-winger meets the left-back of Madrid.
Mohamed Salah – the force behind so much of what Jurgen Klopp’s Reds have achieved this season – faces arguably the best his respective position has to offer, Marcelo.
But despite the Brazil international being no stranger to marking some of the best forwards in the world, Jurgen Klopp is thought to believe he represents a weakness Salah can exploit.
"I am very happy with my work, my teammates too, the coach, the club, my country," Marcelo said, per ESPN.
"I have nothing to prove to anybody.
"I do my work humbly, without disrespecting anybody or talking about their work. But I did not personally see [Klopp] say this, so I cannot answer him. I know that around a final like this, people like to make up things that did not happen."
Marcelo already has three Champions League medals to his name ahead of his team going for a third consecutive crown – something no team has done since Bayern Munich between 1973 and 1976.
When asked directly if his capacity to handle Salah would harm their chances of doing so, the 30-year-old delivered a clear response.
"I know how we have to play, and I know what I must do to help my team," he said.
"For sure, Liverpool are a great team, have had a great season. We cannot just think about two or three of their players, but their collective, as the full team wins games. It will be difficult, like all games this season, last season. Both teams deserve to be here.”
Few Champions League finals have stirred up as much excitement as the one kicking off in less than 12 hours - and Marcelo’s assessment as to why is pretty spot on.
"Both teams attack a lot, and it depends on how the game starts," he said.
"We have in mind what we must do, we are ready for that. But in a final anything can happen. We must wait and see how the game begins, but I believe it will be a great spectacle for those who love football."