Hartlepool are sweating on the fitness of striker Adam Boyd ahead of the clash with League One pacesetters Sheffield Wednesday.
Boyd is suffering from a knee injury and will be assessed on Friday.
Strike partner James Brown has shaken off a similar problem and is set to start, while Fabian Yantorno is in contention for selection after overcoming a back complaint.
Neil Austin (ankle) remains on the sidelines but is pencilled in for a return to training next week.
Ritchie Humphreys was an unused substitute in the midweek Carling Cup defeat to Wigan and remains short of match-fitness following an Achilles problem.
Pools are unbeaten in three league outings this season and Wadsworth was triumphant in his first game as caretaker manager last weekend, a 2-0 win at Yeovil.
Defender Darren Purse is set to make a timely return to the Sheffield Wednesday starting line-up.
Purse missed Tuesday night's 4-2 Carling Cup defeat to Scunthorpe with a calf injury but is likely to take the place of the suspended Richard Hinds.
Hinds saw red against Scunthorpe and will serve a one-match ban this weekend.
Midfielder Tommy Miller is pushing for a place in the starting line-up after coming on to play the final half hour against Scunthorpe following a hamstring strain.
Clinton Morrison played the full game against Scunthorpe after missing the 1-0 win over Brighton last weekend due to a groin problem and should keep his place.
Owls manager Alan Irvine will again be without Jermaine Johnson as the winger continues his rehabilitation after damaging knee ligaments.
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