Boss Brian McDermott could hand a debut to Ian Harte as Reading begin life without Gylfi Sigurdsson against Crystal Palace.
Sigurdsson left the club for Hoffenheim on transfer deadline day for a club record fee and McDermott used a fraction of that to recruit former Leeds defender Harte from Carlisle.
Harte is likely to be on the bench while fellow deadline-day signing Zurab Khizanishvili could make a second debut after re-joining on loan from Blackburn.
The Georgian was a huge hit during his time with McDermott's side last season and he could start at right-back if Andy Griffin is still out with his hamstring injury.
Versatile midfielder Brynjar Gunnarsson started at full-back in the win at Leicester last time out but came off with a hamstring injury and he is a doubt. Matt Mills should be fine after an ankle problem.
Club captain Ivar Ingimarsson and Chris Armstrong played for the reserves this week after lengthy absences but are not ready for consideration while Jay Tabb (ankle) and Julian Kelly (hamstring) are out.
James Vaughan and Anthony Gardner are in line to make their Palace debuts.
Striker Vaughan joined the Eagles on three-month loan deal from Everton on Wednesday and could partner Pablo Counago in attack.
Defender Gardner arrived on transfer deadline day from Hull and could also find himself thrust straight into the starting line-up with Palace having lost their last three Championship matches.
Young forward Wilfried Zaha serves the second game of his three-match ban.
Skipper Paddy McCarthy was forced off during the first half of the defeat at Scunthorpe last time out through illness but has recovered.
Midfielder Darren Ambrose is still out with a leg injury and joins David Wright (calf), Sean Scannell and Lee Hills (both knee) on the sidelines.
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