Carlisle will be without injured skipper Paul Thirlwell for the home clash with Brighton.
The midfielder strained knee ligaments in last week's win at Sheffield Wednesday and will be sidelined for up to four weeks.
Manager Greg Abbott has several options available to him as he looks to re-jig his midfield, with player-manager Graham Kavanagh, Ben Marshall and Matty Robson all ready to step up to fill the void.
Abbott has no other new injury worries, but Marc Bridge-Wilkinson is still struggling with an ankle problem, fellow midfielder Kevan Hurst (back) is not ready for first-team action and Danny Livesey (groin) has targeted a return to full training next month.
Abbott's side, unbeaten at home in the league this season, could leapfrog Peterborough into top spot with victory.
Brighton skipper Gordon Greer returns to the squad.
The defender recently completed a three-match ban but his comeback was then delayed by a calf injury picked up during a practice match.
His return will give manager Gus Poyet a selection dilemma after the Seagulls secured a fine 2-0 win over MK Dons last weekend.
Goalkeeper Peter Brezovan (wrist) and defender Lewis Dunk (foot) proved their fitness in the reserves this week after injury lay-offs so midfielder Alan Navarro (cruciate) is the only long-term absentee.
Poyet is set to recall Argentinian midfielder Agustin Battipiedi, who was omitted from the squad last Saturday but has impressed in training during the week.
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