Francisco Sandaza's injury-time winner fired Brighton to the summit of the npower League One table with a 2-1 win at home to Oldham.
Lewis Alessandra's well-placed 18-yard strike gave Oldham the lead at the Withdean Stadium before Ashley Barnes' powerful header pegged the visitors back.
A fierce second half that saw six players enter the book looked to be heading for a stalemate only for Sandaza to take advantage of Dean Brill's fumble to score his first for the club and send his side top.
An injury-time header from Swindon defender Sean Morrison inflicted a 1-0 defeat on Huddersfield while Peterborough climbed into second with a 2-1 over MK Dons at London Road. Dons defender Dean Lewington levelled Craig Mackail-Smith's opener before Aaron McLean outjumped a packed box to beat David Martin to grab Peterborough's winner.
At the other end of the table Jon Nurse's injury-time header gave Dagenham a 2-2 draw against Charlton at The Valley. Johnnie Jackson had thought he had won it for the home side when he scored to make it 2-1 in the 90th minute after Danny Green's penalty had cancelled out Miguel Angel Llera's opener for Charlton.
Sheffield Wednesday's season went from bad to worse against Southampton at Hillsborough where they suffered their fourth successive defeat thanks to Lee Barnard's 61st-minute winner while Bournemouth bounced back from last week's loss to Oldham by beating Carlisle 2-0 courtesy of goals from Ryan Garry and Michael Symes.
Walsall lost their sixth game in a row with a 2-1 defeat at Hartlepool. Julian Gray gave the Saddlers the perfect start when he put his side ahead after six minutes but any hopes of victory were dashed by Antony Sweeney and Andy Monkhouse, who gave the hosts their first home win of the year.
Rochdale remain in sixth after drawing 1-1 with Plymouth at Spotland with Bradley Wright-Phillips and Craig Dawson trading goals while Will Hoskins' third and fourth goals of the campaign helped Bristol Rovers to brush past Notts County 2-1 at Meadow Lane. Ben Davies scored for County.
A first-half blitz triple strike from Colchester sent Tranmere to the bottom of the table with a 3-1 defeat. David Mooney, Anthony Wordsworth and Magnus Okuonghae all scored before the break and Colchester could have had a fourth had Wordsworth not missed a penalty 10 minutes from time before Enoch Showunmi bagged a consolation goal.
Richard Logan scored twice to help Exeter beat Yeovil 3-1 in the west country derby at Huish Park. Ryan Harley was also on target for the Grecians while Andrew Williams scored Yeovil's only goal of the game.
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