MK Dons boss Karl Robinson will again be short of numbers ahead of the visit of in-form Colchester.
Robinson was without four first-team players for the midweek defeat to Charlton and is set to name the same squad against an unbeaten United side.
On-loan QPR forward Angelo Balanta has a hamstring injury and he will again miss out, while central defender Sean O'Hanlon is out with a knock.
Striker Sam Baldock is out with an ankle injury and midfielder Stephen Gleeson rounds out the injury list as he continues to struggle with a back muscle problem.
Last season's top scorer Jermaine Easter is hoping to earn a recall after coming off the bench at The Valley as Robinson's men look to bounce back from consecutive away defeats.
Colchester will be without left-back Marc Tierney for the trip.
Tierney sustained a dislocated shoulder during Tuesday night's 2-2 draw against Dagenham and could face a long spell on the sidelines.
Boss John Ward has moved for Bristol City defender Tom Williams on a month's loan as cover and he could start.
Captain Magnus Okuonghae needs a late check after suffering concussion against his former club in midweek, but the Us are confident he will be fit.
Fellow centre-half Pat Baldwin could return after missing the last two games with a foot injury but right-back Brian Wilson is still out with ankle trouble.
Midfielder John-Joe O'Toole and defender Morten Knudsen (both knee) remain long-term absentees.
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