Goals from Jordi Gomez and Hugo Rodallega in a 2-0 win lifted Wigan out of the bottom three and condemned 10-man Wolves to a fourth successive Barclays Premier League defeat.
Gomez put the hosts ahead at the DW Stadium with a brilliant free-kick in the 65th minute and Rodallega deflected in a second five minutes from time.
Wolves were up against it from the 11th minute, when captain Karl Henry was sent off for a shocking challenge on Gomez, but it was the Wigan midfielder who had the last laugh.
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