Midfielder Mark Noble will miss the visit of West Brom despite returning to light fitness work this week after having his appendix removed.
Noble was voted as the West Ham fans' Player of the Month for October, but will miss at least the next two home games with Blackpool also due to visit the Boleyn Ground at the weekend.
Fellow midfielders Jack Collison (knee) and Thomas Hitzlsperger (thigh) remain on the long-term injury list while Tal Ben Haim (foot) and Zavon Hines (knee) are also out.
Matthew Upson has told his team-mates that, before they can climb out of trouble, they need to accept their performances so far have warranted their lowly position.
"I think some of our performances have been a mixed bag in the same game, with good and bad that has just cost us in little areas," he told the club's website, whufc.com.
"We've made bad choices and we've been punished heavily this season. We need to get back on a winning streak and a couple of wins will change everything.
"The brutality of the Premier League is that, if you make the wrong choice, you'll pay for it.
"We can't say we're not a 'bottom of the table club' because the facts speak for themselves and we are.
"The table doesn't lie and the points we have don't lie. That's the things we need to change and until we change that, we have to accept that we're in this position and we have to get out of it.
"I think we need to learn from games like Saturday and understand that once we went 2-0 up and our attitude, our decisions with the ball and the way we played the game needed to be different.
"If we'd done that, we'd have won the game."
West Brom will be without suspended midfielder Youssouf Mulumbu.
Mulumbu will have to serve a one-match ban after his sending-off for acquiring two yellow cards against Manchester City on Sunday.
Defender Gonzalo Jara is also suspended as he serves the second of a three-game ban for his straight red card at Blackpool.
Full-back Nicky Shorey is battling to overcome an ankle knock sustained against City.
But Albion boss Roberto Di Matteo is hoping Steven Reid (Achilles) and James Morrison (knee) will be fit.
Scott Carson expects West Brom to return to the kind of performances which have been the trademark for most of the season.
The Baggies have been in the top six of the Barclays Premier League in recent weeks but back to back defeats against Blackpool and Manchester City have seen them drop down to 10th.
Skipper Carson believes Albion showed City too much respect during the opening 45 minutes of their 2-0 home defeat.
He said: "We have been getting into players' faces during games, stopping them playing, and making it difficult for them.
"Against City, we seemed to stand back a bit too much in the first half and maybe showed them too much respect.
"It was something we haven't been doing. We sat off them and invited pressure. We lacked a bit of energy in pressing and closing them down.
"We kept going and should have played how we did in the second half in the first half.
"We have had a good start to the season but Sunday showed we have to be at 100% at all times at this level. Now we have to bounce back."
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