Isco may be regarded as one of the world's best attacking midfielders, but as it stands Real Madrid manager Santiago Solari has no place for the Spaniard in his team.
Since Solari was named as interim manager on October 29 - he took over permanently two weeks later - Isco has played just 78 minutes of football.
And it was the same old story on Tuesday night as Solari completely dropped Isco from his team to face AS Roma, not even including him on the bench.
Clearly the pair aren't seeing eye-to-eye at the moment, with Solari explaining to the media after the 2-0 win that Isco was omitted for sporting reasons.
"There are specific decisions for specific moments," said the Argentine. "We are making decisions and that's it, they are almost always sporting except in rare cases, but that doesn't apply here."
Being completely excluded from the game will have been embarrassing for Isco, who even had to ask a club official before the game if he was allowed to enter the dressing room.
What the future now holds for the 26-year-old remains to be seen but he's received some rather contrasting messages from some of his teammates.
Toni Kroos and Marcelo were both asked for their thoughts on Isco and whereas Kroos played it safe by saying it was the manager's decision, Marcelo gave Isco some tough love.
"It's a decision by the coach who has his reasons, I can't change things," said Kroos. "We all know the type of player Isco is. He has had great matches for this team."
And Marcelo said: "Every player wants to play, but you have to work hard. I'm not anyone to give advice, we're old enough, parents, and we all know what we have to do.
"It's happened to all players. You have to work. I am not saying Isco doesn't, but this is football. Look at where you are falling short and improve."
Fair play to Marcelo - the Brazilian could have gone easy on Isco by saying he will get back into the team, but instead he told the Spain midfielder to pull his socks up and work harder.
Should things not work out for Isco under Solari then a move to the Premier League may be on the horizon, with Chelsea and Manchester City reported suitors.
Arsenal are also interested, while Manchester United could do with a player of Isco's quality as they continue to struggle for goals.