Oxford manager Chris Wilder is without the suspended Tom Craddock for the visit of Shrewsbury.
The striker serves his one-match suspension after picking up his fifth yellow card of the season against Barnet and is unavailable.
Defender Leigh Franks limped out of a reserve-team game with a tight hamstring and may miss Saturday's game which leaves Harry Worley and Ben Futcher as the U's only recognised central defenders.
The break for bad weather has helped Jake Wright's recovery from a foot operation. The defender is likely to make a return to action in the new year which is earlier than first thought.
Striker Matt Green, midfielder Asa Hall and defender Ben Purkiss all represented the reserves in midweek in order to stake a claim for a return to Wilder's starting line-up.
Shrewsbury will be without Benjamin van den Broek for the trip while Andrew Tutte has not yet recovered from injury.
Midfielder Van den Broek, a second-half substitute in last weekend`s 1-1 draw against Cheltenham, damaged knee ligaments while playing for Town`s reserves in midweek and is facing four to five weeks on the sidelines.
Loan signing Tutte missed the chance to make his debut against the Robins having been struck down with a back problem, and although he made a return to training at the start of this week he suffered an adverse reaction and will again watch from the sidelines.
Craig Disley, another midfield casualty for boss Graham Turner, has discovered his hip injury is worse than first feared and may require surgery, meaning he also misses out at the Kassam Stadium.
Winger Lionel Ainsworth is in line for more game time having made an 11-minute cameo upon his return from a groin injury last Saturday.
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