Leyton Orient duo Elliot Omozusi and Adam Chambers are doubts ahead of the visit of MK Dons.
Full-back Omozusi and midfielder Chambers missed Saturday's 4-0 win over Sheffield Wednesday with hamstring injuries and are unlikely to be ready in time.
Boss Russell Slade will be tempted to name an unchanged line-up following their weekend romp.
On-loan Tottenham teenager Harry Kane started in place of veteran frontman Scott McGleish and marked his full debut with his first senior goal.
Midfielder Matt Sparrow (knee) and striker Jonathan Tehoue (hamstring) were involved despite their recent niggles and came through unscathed.
Romanian forward Adrian Patulea left the club over the weekend after his contract was cancelled by mutual consent.
MK Dons will be without striker Sam Baldock.
Baldock made his return from a hamstring injury as a substitute at Dagenham & Redbridge on Saturday but lasted just 15 minutes before hobbling off again to leave manager Karl Robinson frustrated.
Robinson said: "It's not yet clear how long he's going to be out but he won't travel to Orient in midweek."
Defender Gary Mackenzie missed out at the weekend with a head injury but could be fit enough to return while Mat Doumbe came through the full 90 minutes at Dagenham after a head injury of his own.
On-loan QPR striker Angelo Balanta will be out of action until March with an ankle problem while fellow Rangers forward Rowan Vine will again be on the bench after joining the club last week.
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