Aside from arguably being the biggest clubs in the realm, they have dominated the top places to such an extent in recent seasons that they have become known as the 'top six' in their own right.
Sure, the likes of Leicester City and Wolverhampton Wanderers will be hoping to change that, but they have the disadvantage of much lower transfer budgets and far shallower squad depths.
And while Tottenham and Liverpool are still waiting for their first Premier League titles, the remaining four sides have won 25 of the 27 seasons that have taken place since the 1992 inauguration.
So, aside from Leicester and Blackburn Rovers' anomalous victories, there hasn't been that much variety in the Premier League champions.
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The Premier League without the top six
That gave us an idea: what if the Premier League's top six never competed? It's an incredibly complicated question, but one made far easier by Transfermarkt's customisable table tool.
We have removed the top six from every single season, thus eradicating any results or points that involved them, and seen how the tables would have played out in their absence.
The biggest winner is Everton with eight trophies, Newcastle are in second with six wins and then the likes of Norwich City, Burnley and Southampton pop up with surprise victories.
Check out the full breakdown of all 27 seasons down below: