Is there a bigger game in the Premier League than Manchester United vs Liverpool?
English football's two red religions lock horns once again on Sunday with the Merseysiders overwhelming favourites to claim three points.
For United, a win at Old Trafford would be a mighty upset but could be the spark they need to ignite their stuttering season.
Liverpool will be looking to extend their unblemished start to the season with a win - matching Manchester City's record for most consecutive league wins in the process.
Old Trafford has not been a happy hunting ground for Liverpool over the years though - while Jurgen Klopp's record at the Theatre of Dreams is less than impressive.
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There is just something in the water at United's mythical home that makes a Liverpool player struggle and it has been that way for decades.
Back in the days when United were dominating the English football landscape, a certain Gary Neville was the tormentor in chief of the Anfield faithful.
Speaking ahead of Sunday's titanic clash, former Liverpool striker Peter Crouch recounted the moment he realised exactly why Kopites hated Neville so much.
"I knew Gary Neville was the Manchester United player Liverpool fans loved to hate and in that sickening moment - in the 94th minute of a game at Old Trafford on Sunday, January 22, 2006 - I understood why.
"Never before had an opposing player p***** me off so much with a celebration.
"I had been substituted and was sitting in the dugout, and from that angle, it felt like he was coming to rejoice in front of me.
"Here was my proper introduction to the biggest rivalry in English football, in what was my first season as a Liverpool player."
After Rio Ferdinand thundered a header home with one of the last acts of the game, Neville legged the full length of the pitch to celebrate in front of the travelling Kop.
Neville was the king of the wind up when it came to Liverpool fans, wasn't he?
Now though, the shoe is on the other foot and Klopp's juggernaut will be desperate to write their own piece of history in this mammoth clash.
Beware the wounded beast though - United won't be about to lightly let their greatest rivals storm their home and walk away unscathed.
It's a clash of the titans and the Theatre is the stage - we can't wait.