The Frenchman joined from Atletico Madrid in the summer and was expected to hit the ground running at Camp Nou, but he's not yet on the same wavelength as his teammate.
That was very clear in Barca's 0-0 draw with Slavia Praha on Tuesday night, when Messi made just four passes to Griezmann, while Griezmann astonishingly made just one.
Certainly not the kind of chemistry supporters expected to see, especially four months into the season.
Since the winger's arrival, there have been plenty of reports suggesting the pair simply don't get on for one reason or another.
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And now, El Chiringuito have reported that Messi and Griezmann don't even speak in training, which will add further fuel to that fire.
Check out the clip below:
The latest suggestions will certainly concern Barca fans and that might not even be the worst of it.
According to L'Equipe, per News18, Griezmann has an equally rocky relationship with Luis Suarez.
Their report suggests that the Blaugrana's two biggest stars still haven't forgotten about their new teammate rejecting a move to the club in 2018.
It adds that the pair simply just ignore the World Cup winner, which is pretty brutal.
Despite all these reports, Gerard Pique has recently moved to squash any rumours of a rift in the squad.
"It's really good," he said of Messi's relationship with Griezmann.
"Leo and Antoine get on just like Leo does with Dembele or Pedro or Villa. They get on well. With Luis, they're practically like brothers and then after that there are different relationships.
"Just because he doesn't get on with Griezmann like he does with Luis doesn't mean they don't get on well."
We're not sure we believe you on this one, Gerard.News Now - Sport News