After a long international break which saw England qualify for the knockout stages of the Euros, attention turns back to domestic football this weekend and a full line-up of Premier League fixtures.

Last time out, we saw Liverpool dispatch Man City at Anfield and extend the gap at the top of the table to eights points, and home wins for both Chelsea and Leicester saw the two sides move above City into second and third position.

Watford dug deep and secured a vital three points away at Carrow Road, which moved them off the bottom of the table and into 18th spot.

Tottenham’s miserable run continued with a home draw against Sheffield United, which was the final nail in the coffin for Spurs chairman Daniel Levy, who controversially sacked manager Mauricio Pochettino on Tuesday night after a five-year stay.

Levy wasted little time in naming his replacement, as on Wednesday morning Jose Mourinho was announced as the new Spurs head coach.

Eleven months after being sacked by Manchester United, the ‘Special One’ returns to the dugout at the London Stadium on Saturday when his new Tottenham side play West Ham.

Here is our preview of the upcoming Premier League fixtures, with a few helpful tips from GIVEMEBET along the way.

Saturday

West Ham vs Tottenham

Saturday’s lunchtime fixture between West Ham United and Tottenham Hotspur at the London Stadium just got a lot more interesting…

It’s the return of Mourinho, who Spurs have announced as their new manager following the sacking of Pochettino.

Spurs fans are divided, but it will be fascinating to see if the ‘Special One’ can turn their season around after a shocking few months which sees them buried in the bottom half of the table.

(GMB odds - Spurs to win 20/27)

Arsenal vs Southampton

Arsenal welcome Southampton to the Emirates Stadium on Saturday afternoon as the Gunners look to record their first win in four league games.

Unai Emery’s side currently occupy sixth place and a poor run of results sees Arsenal sit eight points adrift of the Champions League places.

Southampton have lost their last three Premier League outings and will be desperate to climb out of the relegation zone with an unlikely victory over the Gunners.

(GMB odds - Southampton to win 11/2)

Bournemouth vs Wolves

There has been little to separate Bournemouth and Wolves in the Premier League so far this season.

Both sides have collected 16 points and sit in the top half of the table, giving both sets of fans hope of pushing for European qualification by the end of the campaign.

(GMB odds - Score draw 3/1)

Brighton vs Leicester City

Leicester make the trip to the Amex Stadium to face Brighton looking to retain their hold of second position in the Premier League table.

However, the Seagulls welcome the east Midlands outfit having recorded victories in each of their last three home matches in the top flight.

(GMB odds - Leicester to win 1/1)

Crystal Palace vs Liverpool

Liverpool’s title challenge continues when they travel to Crystal Palace on Saturday afternoon.

The Reds beat Manchester City 3-1 before the international break to open up a nine-point lead over Pep Guardiola’s men, while they sit eight clear of Chelsea and Leicester.

Palace will be looking for a statement win against the Premier League leaders after going four games without a win and will be sure to make life difficult for Jurgen Klopp’s side at Selhurst Park.

(GMB odds - Liverpool to win & BTTS 19/10)

Everton vs Norwich City

Everton host Norwich City on Saturday in a must-win encounter for Marco Silva’s men.

The Toffees sealed a vital 2-1 victory over fellow strugglers Southampton before the international break and with a run of fixtures featuring Leicester, Liverpool, Chelsea, Man United and Arsenal to come, three points against the Canaries is non-negotiable.

But while Everton’s situation seems precarious, things are becoming quite desperate for Norwich. Daniel Farke’s men have taken just one point from their last seven games since a shock win over Man City in September and are now rooted to the bottom of the Premier League.

(GMB odds - Everton to win to zero 7/5)

Watford vs Burnley

Watford welcome Burnley to Vicarage Road on Saturday afternoon with both sides looking to make it back-to-back wins in the Premier League.

Sean Dyche’s Clarets currently sit 10th in the table, eight places and seven points above Quique Sanchez Flores’ Hornets.

(GMB odds - 0-0 draw 15/2)

Manchester City vs Chelsea

Pep Guardiola knows he can’t afford to slip up against Frank Lampard’s high-flying side after seeing Liverpool open up a nine-point gap on them before the international break.

The Blues have been one of the surprise packages of the season thus far, and are looking for a club record eighth consecutive away win in all competitions.

(GMB odds - Man City to win & BTTS 27/20)

Sunday

Sheffield United vs Manchester United

Ole Gunnar Solskjaer will be hoping to keep United’s mini-revival alive as the Red Devils face a tough trip to Bramall Lane on Sunday afternoon.

The Blades are riding high in fifth position with 17 points from 12 games and have proven their worth in the top tier of English football.

United currently sit nine points off fourth-placed Manchester City, meaning that winning the Europa League looks the likeliest route back into the Champions League at this point.

(GMB odds - Sheffield United to win 51/20)

Monday

Aston Villa vs Newcastle United

Aston Villa will want to move away from the relegation zone on Monday night when they play host to Newcastle United.

However, if Newcastle were to win, they'd move up to 18 points from their first 13 games. Not bad for Steve Bruce's men.

(GMB odds - Draw 5/2)