Duncan Ferguson's Everton left Old Trafford with a highly-satisfactory point after playing out an entertaining 1-1 draw with Manchester United.

The match may well be remembered for a baffling substitution made by the interim Everton boss at the end though, when he took striker Moise Kean off despite having brought him on only minutes earlier.

Much had been made of Everton's threadbare squad before kick-off, with illness and a number of injuries meaning that it had a lopsided look, with an abundance of strikers but a shortage of central midfielders.

And these lack of options meant that Kean was brought on for midfielder Bernard after 70 minutes, despite the visitors leading 1-0.

What was more surprising though, was that when the fourth official's board was raised again in the 89th minute, to Kean's disbelief, his number was on it in red this time.

Moise Kean substituted just minutes after coming on against Manchester United

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Needless to say, the former Juventus striker was as baffled as fans and pundits alike, and ignored his manager before heading off straight down the tunnel.

Ferguson later justified the substitution.

"It wasn't because of Moise Kean's performance.

"I just needed to make a substitution to kill a bit of time. I had so many strikers on the bench. It's nothing personal against Moise Kean."

Here is a list of other substitutions that have left players furious and stadiums stunned.

Jasper Cillessen

With the Netherlands' match against Costa Rica in the 2014 World Cup going to penalties, Louis van Gaal made the bold call of replacing his no. 1 keeper Jasper Cillessen with Tim Krul just for the shootout.

Krul, of Newcastle at the time, had only saved two of his 20 penalties for the club, so the decision surprised many.

Van Gaal was seen as a genius minutes later though, with Krul's two penalty saves sending the Dutch into the last four against Argentina.

Juan Mata

The Spaniard may have feared the worst when old boss Jose Mourinho was appointed Manchester United boss having sanctioned the sale of Mata to them when he was in charge of Chelsea.

And their renewed partnership got off to a bad start during the first game of the season. With United leading 2-1 against Leicester City in the dying seconds of the 2016 Community Shield final, Mourinho replaced Mata with Henrikh Mkhitaryan because “he was the shortest player on the pitch, and more high balls were coming into the box”.

Mata’s replacement Henrikh Mkhitaryan was 7 centimetres taller and did not participate in any aerial duel for the remainder of the game, which United saw out.

Mario Balotelli

Balotelli enjoyed action-packed spells with Manchester City and Liverpool, where he rotated between brilliant and ridiculous with ease.

One of the low points during his time at City came at Anfield when he replaced the injured Carlos Tevez, but after another infuriating display, Roberto Mancini subbed him off for Nigel de Jong in the 83rd minute, with Liverpool going on to win 3-0.

Nemanja Matic

Jose Mourinho strikes again. During his second stint at Chelsea, he was experiencing his usual third-season troubles having won the title the season before.

Losing 3-1 at home to Southampton, the Portuguese boss replaced Matic with Loic Remy despite having only brought him on at half-time for Ramires.

Emmanuel Eboue

“Eboue played for longer than I wanted him to" was Arsene Wenger's frank assessment of his defenders performance against Wigan in 2008.

The Ivory Cost international replaced an injured Samir Nasri but was then taken off for Mikael Silvestre in stoppage time.

Eric Dier

It seems like Jose Mourinho really doesn't care about making awkward calls.

Seeing his new Tottenham Hotspur side trailing 2-0 at home to Olympiacos, Mourinho took off Dier for the more attack-minded Chrstian Eriksen.

Mourinho's decision was vindicated, with Spurs staging a great comeback to win 4-2 in his first home game in charge for the club.

Eric Bailly

And Jose makes his fourth appearance in this rather unique list.

With Manchester United's defence all over the place at home to Newcastle, Mourinho replaced the struggling Eric Bailly after just 19 minutes with Juan Mata, who found himself on the right side of such a substitution this time.

Again Mourinho got it spot on as United staged a comeback to win 3-2 with Mata getting the first of those goals.

Joe Cole and Shaun Wright-Phillips

The final Jose Mourinho feature, honestly.

During his first spell at Chelsea, he made a double substitution after 26 minutes with his side losing 1-0 at home to Fulham.

Both Joe Cole and Shaun Wright-Phillips were hooked for Didier Drogba and Damien Duff, but they still lost.

Haim Megrelashvili

Megrelashvili's entry is interesting as it actually happened to him twice in consecutive matches.

Vitesse boss Aad de Mos hauled Megrelashvili off just six minutes into a 4-3 defeat to Twente and then substituted Megrelashvili after 15 minutes in the next game.

Not even Mourinho would have the heart to do that, surely.

To rub salt into the wounds, he would tell the club’s official website that the switch was “too late”, with Vitesse going on to losing 2-1.

Claudio Caçapa

Sam Allardyce is probably still seething at this one.

Newcastle found themselves 3-1 down to Portsmouth and Caçapa was seen as one of the major reasons for that, with the centre-back being replaced after only 18 minutes in November 2007.