This weekend, reigning champions Liverpool face a Manchester United side that have somewhat surprisingly emerged as their biggest challengers in this season's Premier League title race.
Indeed, a slump in results from Jurgen Klopp's side coupled with an uplift in form from Ole Gunnar Solskjaer's boys has left the Reds three points behind the Red Devils, who even have the privilege of entering Sunday's encounter in first place.
That will only add to the heat, intensity and importance of perhaps the greatest fixture in the history of English football and the Premier League's closest comparison to El Clasico.
Indeed, the Northwest derby (albeit not recognised as such back then) can be traced back to the 19th century, and since that first meeting Liverpool and Manchester United have both enjoyed periods of prolonged dominance over the rest of English football.
The latest instalment has all the makings of a cracker, then. But are you a fair-weather follower with a passing interest, or do you really know your stuff when it comes to the Northwest rivalry?
Find out below by taking on our ultimate Liverpool vs Man United quiz - and don't forget to share your score on social media!