Aston Villa boss Alex McLeish has confirmed that both Emile Heskey and Jermaine Jenas will miss this weekend's clash against Newcastle.
The pair join Eric Lichaj on the sidelines, with last season's Leeds loanee out for three to four months after undergoing surgery on a hip injury.
It's an undoubted blow to the Scottish boss ahead of the Magpies' visit to Villa Park, although Jenas is expected to return for the midweek Carling Cup clash against Bolton.
"Emile's got a nick in his hamstring and that's not an overnight job, so it will be a few weeks - two to three, maybe even longer. Whether he's a quick healer, I don't know his history," McLeish told the official Villa site.
"Jermaine has had some treatment and we're hopeful that the treatment will allow him to be involved in next week's cup game. He's very keen to go. He's disappointed. He felt the nick last Thursday but thought he could get through Friday's training. His keenness to impress has given him a little bit of a setback but he will be more careful next time.
"Eric had an operation on his hip. It was successful, but he'll be out for three or four months. Again that's a blow.
"We could ill afford to lose vital members from the squad but it's a challenge for somebody else."
Some positive news for the former Birmingham boss is the gradual return of Carlos Cuellar, with the Spanish defender recovering well from a long-standing knee injury.
"Carlos is coming back to some sort of semblance of fitness," continued the Villains chief.
"He'll have a wee bit of catch up in terms of match fitness."
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