Bottom of the league Doncaster Rovers host leaders Southampton on Saturday in a fixture of contrasting needs.
Doncaster need inspiration to begin to climb from rock-bottom and midfielder Simon Gillett believes they could get a much-needed confidence-boosting win: "We've got as good a chance to beat them as anyone else. We will be going out there to get the three points on Saturday."
The former Saints player had nothing but praise for his ex-club: "It's the match I was most looking forward to.
"I'm not surprised at how well they have done this season they're a fantastic club, with the setup and management they've got, they belong in the Premier League."
A win for Saints will ensure them top spot although West Ham are just two points behind going into the weekend.
The Hammers take on Burnley on Saturday off the back of four-successive wins and will look to stay breathing down the neck of Southampton. A win for 14th placed Burnley could move them up to as high as 9th, depending on other results.
Elsewhere in the Championship Hull City host Leicester - a match that sees new Foxes boss Nigel Pearson return to his former club. Two points seperate the sides and a win for the Tigers could see them move into the play-off places at Leicester's expense.
Reading [9th] travel to Blackpool [8th] to feature in another game that has play-off place potential. With both teams on 27 points it is a five way race for 6th spot along with Brighton who are in 7th with 29 points.
Brighton, off the back of two wins, take on Nottingham Forest who after last-week's loss see themselves slip into the bottom three.
High-flying Cardiff, who are in third place, do not play until Sunday when they face 11th-placed Birmingham City. The Welsh side will look for three points in a bid to close the gap between them and Southampton - which could rise to nine points.
Fifth-placed Leeds host Millwall in Saturday's early kick-off, presenting a chance for Leeds to go level with Cardiff in third.
A confident Crystal Palace side will look to emulate their Carling Cup win over Manchester United as they face Derby County on Friday night. A win for the Rams will see them pass Palace in the League standings.
Forth-placed Middlesborough take the long trip down south to Bristol City. A loss for the Robins could see them occupy a place in the relegation zone.
The remaining three games see Ipswich take on Watford with all to play for as just one point seperates the sides. Barnsley take on Peterborough in a mid-table clash with both sides on 24 points, while Portsmouth take on lowly Coventry City at Fratton Park.