Sir Alex Ferguson is confident his Manchester United squad is strong enough to cope with the current injury problems affecting the side.
Javier Hernandez and Dimitar Berbatov are two high-profile absentees ahead of tonight's crucial trip to Basel, whilst the Da Silva twins are also out alongside Michael Carrick, who is suspended for the tie.
Academy graduates Ezekiel Fryers and Larnell Cole traveled in the 22-man party heading for St. Jakob-Park, and Ferguson is in no doubt that his side are ready for the Group C clash.
"We've played a lot of big games. Tomorrow is another," said Ferguson during his pre-match press conference.
"People say we're not doing well but we're second in the league and we can qualify for the last 16. Injuries haven't helped but we have a strong squad and the squad will see us through."
Basel have been left in no doubt that they can cause an upset though, with midfielder Scott Chipperfield admitting confidence is high following the 3-3 draw at Old Trafford.
The Australian international is amongst a host of players who could cause the Red Devils problems, and expects the Swiss champions to be in with a chance of taking all three points and stealing the final qualification spot behind Benfica.
"You know all about United when you play them and you're also really motivated to do well. You look forward to games like that, particularly young players," he told the official United website.
"For them, high-profile opponents gives them a chance to showcase their skills in front of a lot of important people. When United come to Basel we'll all be up for it and we're looking to pull off an upset."