Manchester City were left facing a huge task to revive their Champions League campaign after crashing to a 3-1 defeat at Ajax.
Samir Nasri put them on course for victory in their vital Group D game in Amsterdam with an early strike but it came much against the run of play.
Ajax responded emphatically to get their first win of the competition - and leave City still looking for theirs - with goals from Siem de Jong, Niklas Moisander and, with the aid of a deflection, Christian Eriksen.
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