Fabregas' chances at the Nou Camp have been limited since his arrival two seasons ago, and following Barcelona's capture of Brazilian superstar Neymar, the Spaniard could look for a move to ensure regular football.
David Moyes has reportedly targeted the midfielder as his number one priority and has lined up a £40m bid. The Scot is looking to stamp down a signal of intent with a major signing and Cesc fits the bill, his calibre and Premier League experience vital factors.
But it is not just United that are interested, Fabregas is drawing strong interest from his former club Arsenal. The Gunners have a buy-back clause in his contract and will be offered first refusal should Barca decide to offload the player.
The former Arsenal captain was a fans' favourite at the Emirates Stadium, becoming the club's youngest ever captain - and it was in north London where the 25-year-old has played his best football of his career thus far.
Here, we weigh up the reasons for joining United or Arsenal
Linking up with former compatriot Robin van Persie at Manchester United could be very appealing: during their times at Arsenal, the pair produced an almost telepathic relationship at times.
Van Persie's decision to quit the Gunners last season for bitter rivals United resulted in a title win in his first season. The Dutchman had only won one FA Cup during his eight-year spell under Arsene Wenger.
Fabregas may also be swayed by the strong chance of regular football. Following Paul Scholes' retirement there is a gap in United's midfield, a potentially mouth-watering partnership with Michael Carrick could be a real attraction.
Unlike Arsenal, Old Trafford will present Cesc with an entirely new challenge. He will be arriving at a club that is proven in winning trophies and he may feel that he can become a real talisman. Something he has found hard at Barcelona; not surprising, though, when the Catalan club boast Lionel Messi in their ranks.
Likewise, though, returning to London would similarly see Cesc once again become the club's main man.
Throughout his time with the Gunners Wenger would often build teams around the Spanish international and, in doing so, Cesc truly flourished.
Fabregas has repeatedly expressed his admiration for his former boss and claims that he is like a second father, an opportunity to once again work with Wenger may pave the way for a move back.
There is a familiarity in returning to the Emirates and he could pave the way for more stars to follow him to London.
The likes of Gonzalo Higuain, Wayne Rooney and Marouane Fellaini have been linked as Wenger finally looks ready to plough through a £70m war chest. A midfield of Fabregas, Fellaini and Jack Wilshere would also put fright into any opposition.
The Barcelona playmaker may remain in Spain for at least one more season but should he return to England, will he be moving north or south?
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