Manchester United forward Robin van Persie is a serious doubt for Holland's two remaining World Cup qualifying games, according to ESPN.
The striker sustained a toe injury - at first thinking it was broken - in United's 1-1 draw in Donetsk, however he played through the pain for his club as they came back from a goal behind to defeat Sunderland.
Though the Netherlands have already qualified for the 2014 World Cup, the former Arsenal man is only three goals short of becoming his nation's all-time leading goalscorer.
Securing the three goals needed to eclipse Patrick Kluivert's record haul of 40 goals was a genuine possibility for van Persie during the two upcoming fixtures, though he may now have to wait.
"I got an enormous stamp on my toe and I really thought it had been broken, but luckily a scan showed it was not," he said.
"I played on Sunday but the injury has not got better."
Van Persie has yet to hit the form that saw him play a major role in United's 20th league title, though the Dutchman does still have three goals in six Premier League appearances so far this season.
Holland, meanwhile, having qualified for Brazil, will be looking to go one step further than the last World Cup when they were defeated by Spain in South Africa.
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