2. Ledley King
Ledley King announced his retirement from football in 2012 after suffering from chronic knee problems for almost the entirety of his career.
Fast, powerful and an exceptional reader of the game, King on his day was among the finest centre-backs the country has seen.
The former Tottenham captain didn't even train with his team-mates for much of his career.
His several knee injuries left him with virtually no cartilage in the joint, although it wasn't just his knee that hampered his career.
He also broke his metatarsal and suffered a number of niggling injuries alongside his constant knee problem
The natural successor to Sol Campbell, Spurs fans will at least take comfort in the fact that his injury troubles kept away neighbours Arsenal.