On Sunday at noon, Andre Villas-Boas will face a critical moment in his career, as his Tottenham take on an inspired Manchester United side.
The reigning champions produced their best performance of the season against Bayer Leverkusen, who they beat 5-0 in the Champions League.
Tottenham, on the other hand, were thrashed 6-0 by Manchester City last weekend and now definitely need a victory to help their manager keep his job.
Striker Emmanuel Adebayor is a doubt for the match, because of a groin injury.
Midfielder Christian Eriksen, defender Danny Rose and striker Harry Kane have all been ruled of the derby.
Jermain Defoe, Paulinho and Kyle Walker are all expected to return for the match, after being rested for the Europa League game against Tromso.
Manager David Moyes will face a tricky selection before Sunday's clash.
His side thrashed Bayer Leverkusen and Japanese playmaker Shinji Kagawa was instrumental in their victory after finally playing as an attacking midfielder.
Marouane Fellaini is available after suspension, while Robin van Persie and Nemanja Vidic "have a chance" of being available.
Andre Villas-Boas: "They are on a good run that changed their fortunes. We don't expect an easy match, but it will be a completely different story (for United's win over Leverkusen) on Sunday. I'm not being disrespectful, but it will be a different game in different conditions and our players will be mentally ready.
David Moyes: "The best is to come and I still think we can continue to improve and progress. We had some little bits of inconsistency at times, which we need to try to do better with, but there have been moments that have shown we are beginning to come right back into form. That is what I hope. Midweek certainly showed what we are capable of when we are playing well and the job is to do that week in, week out."
Spurs have kept seven clean sheets this season, more than any other team in the
Tottenham Hotspur have won just one of the last 24 Premier League matches against Manchester United.
If Tottenham fail to score, they will equal their worst ever run of games without scoring in Premier League history.
Tottenham: Lloris, Vertonghen - Kaboul - Chiriches - Walker, Sandro - Paulinho, Lennon - Holtby - Lamela, Soldado.
Manchester United: De Gea, Evra - Vidic - Evans - Rafael, Cleverley - Jones, Welbeck - Kagawa - Valencia, Rooney.
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